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KMID : 0359020060330040230
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Korean Journal of Gastrointestinal Endoscopy
2006 Volume.33 No. 4 p.230 ~ p.234
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Two Cases of Gastric Mucosal Calcinosis
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Yeo Ju-Chun
Eum Sung-Woo
Lee Se-Young
Ju Dong-Uk
Lee Jai-Hyun
Kim Se-Hwan
Park Chang-Keun
Lee Seung-Yeob
Kim Hyun-Soo
Koo Mi-Jin
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Abstract
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Gastric mucosal calcinosis (GMC) is a very rare condition that is characterized by the nodular deposition of calcium salts in the gastric mucosa. It has been associated with renal failure, gastric cancer, ingestion of aluminum- containing antacids and the use of sucralfate in organ transplant patients. The etiology of this condition is uncertain, but several theories have been proposed; the condition is due secondarily to hyperparathyroidism in renal failure and to the alkalinization of the gastric mucosa. We report here on two patients who had long-term use of bismuth and/or aluminum-containing antacids to treat their gastro-esophageal reflux symptoms. The esophagogastroduodenoscopy revealed acute gastritis patterns, and GMC was confirmed histologically with biopsy. When one patient stopped ingesting bismuth-containing antacid solution, the follow-up esophagogastroduodenoscopy and the biopsy revealed a completely improved state. We report here on these interesting cases and we include a brief review of the literature.
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KEYWORD
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Gastric mucosal calcinosis, Bismuth, Aluminum-containing antacids
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